Motor Neuropathy Complete Antibody Panel

Test Code
90137

CPT Codes
82784 (x3), 83520 (x6), 86334, 86335 

Includes
Immunofixation (IFE); Immunoglobulins Panel; Ganglioside GM-1 Antibodies (IgG, IgM), EIA; Ganglioside GD1a Antibody (IgG), EIA; Ganglioside GD1a Antibody (IgM), EIA; Ganglioside Asialo-GM-1 Antibody (IgG), EIA; Ganglioside Asialo-GM-1 Antibody (IgM), EIA; Immunofixation (IFE), Urine

Preferred Specimen
5 mL serum and 25 mL random urine (no preservative)

Patient Preparation
Overnight fasting is preferred

Minimum Volume
2 mL serum and 10 mL random urine

Other Acceptable Specimens
Serum and 24-hour urine (no preservative)

Instructions
Serum and urine are required.
Shipping frozen is acceptable.

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Serum
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 30 days

Urine
Room temperature: 5 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Plasma is unacceptable • Serum received at room temperature

Methodology
Immunofixation • Immunoturbidometry • Immunoassay (IA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up and Report available: See individual assays

Reference Range
See Laboratory Report

Clinical Significance
The panel includes ganglioside antibodies associated with motor neuropathies. Many of the anti-ganglioside antibodies associated with chronic immune neuropathies are monoclonal IgM antibodies. An evaluation for monoclonal gammopathy should be performed in this setting.

Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92690-6130



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.