Motor Neuropathy Complete Antibody Panel

Test Code

90137

CPT Codes
82784 (x3), 83520 (x6), 86334, 86335 

Includes

Immunofixation, Serum
Immunoglobulins Panel, Serum
Ganglioside GM-1 Antibodies (IgG, IgM), EIA
Ganglioside GD1a Antibody (IgG), EIA
Ganglioside GD1a Antibody (IgM), EIA
Ganglioside Asialo-GM-1 Antibody (IgG), EIA
Ganglioside Asialo-GM-1 Antibody (IgM), EIA
Immunofixation (IFE), Urine

Preferred Specimen

5 mL serum and 25 mL random urine (no preservative)

Patient Preparation
Overnight fasting is preferred

Minimum Volume

2 mL serum • 10 mL random urine

Other Acceptable Specimens

Serum and 24-hour urine (no preservative)

Instructions

Serum and urine are required.
Shipping frozen is acceptable.

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Serum
Room temperature: 24 hours
Refrigerated: 7 days
Frozen: 30 days

Urine
Room temperature: 5 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Plasma is unacceptable • Serum received at room temperature

Methodology
Immunofixation • Immunoturbidometry • Immunoassay (IA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up and Report available: See individual assays

Reference Range

See Laboratory Report

Clinical Significance

The panel includes ganglioside antibodies associated with motor neuropathies. Many of the anti-ganglioside antibodies associated with chronic immune neuropathies are monoclonal IgM antibodies. An evaluation for monoclonal gammopathy should be performed in this setting.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.