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Quinidine
Test Code766
CPT Codes
80194
Preferred Specimen
1 mL serum collected in a red-top tube (no gel)
Patient Preparation
Collect just prior to next dose
Minimum Volume
0.2 mL
Other Acceptable Specimens
Plasma collected in: Sodium heparin (green-top) tube, lithium heparin (green-top) tube, or EDTA (lavender-top) tube
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube (SST)
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon-Sat; Report available: 1-3 days
Reference Range
2.0-5.0 mg/L
Clinical Significance
Quinidine is used in the treatment of acute and chronic supraventricular arrhythmias and ectopic rhythm disturbances. Quinidine clearance can be altered by changes in plasma proteins and in renal and/or hepatic dysfunction. Both quinidine and the related isomer quinine possess antimalarial schizonticide activity. Quinidine levels are monitored to assure adequate therapeutic levels are achieved and to avoid toxicity.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153