Celiac Disease Comprehensive Panel, Infant [15981X]

Test Code
15981

CPT Codes
82784, 83516 (x2)

Includes
Tissue Transglutaminase (tTG) Antibody (IgA)
IgA
Gliadin (Deamidated) Antibody (IgA)

If Tissue Transglutaminase (tTG) Antibody (IgA) is Detected, then Endomysial Antibody Screen (IgA) will be performed at an additional charge (CPT code(s): 86255).
If the Endomysial Antibody Screen (IgA) is Positive, then Endomysial Antibody Titer will be performed at an additional charge (CPT code(s): 86256).

If Immunoglobulin A is less than the lower limit of the reference range, based on age, then Transglutaminase (tTG) Antibody (IgG) will be performed at an additional charge (CPT code(s): 83516).

Preferred Specimen
5 mL serum

Minimum Volume
1.1 mL

Instructions
This Panel is for patients less than 4 years old. Test Code 19955 Celiac Disease Comprehensive Panel, should be used for adults, patients 4 years and older.

Transport Container
Plastic screw-cap vial

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 21 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic

Methodology
See individual tests

Setup Schedule
Set up: Mon-Fri a.m.; Report available: Next day

Reference Range
(tTG) Antibody, (IgA)
<4 U/mL No antibody detected
≥4 U/mL Antibody detected

Gliadin (Deamidated) Antibody (IgA)
<20 Units Antibody not detected
≥20 Units Antibody detected

IgA, Serum
Cord Blood 1-3 mg/dL
1-28 days 2-40 mg/dL
1-3 months 3-40 mg/dL
4-6 months 7-47 mg/dL
7-11 months 12-53 mg/dL
1 year 20-73 mg/dL
2 years 20-99 mg/dL
3-5 years 22-140 mg/dL
6-8 years 31-180 mg/dL
9-11 years 33-200 mg/dL
12-16 years 36-220 mg/dL
17-60 years 47-310 mg/dL
≥61 years 20-320 mg/dL


Clinical Significance

This panel assists in differentiating celiac disease from other inflammatory bowel diseases and helps avoid progression of celiac disease, particularly in children, through early identification of gluten sensitivity.



Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.