Cyclosporine A Peak (2 Hour), Blood

Test Code

CPT Codes

Preferred Specimen
2 mL whole blood collected in an EDTA (lavender-top) tube

Patient Preparation
Collect as a peak 2 hours post dose

Minimum Volume
1 mL

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: 7 days
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Clotted specimens

Immunoassay (IA)

Setup Schedule
Set up: Daily; Report available: 2 days

Reference Range
No definitive therapeutic or toxic ranges have been established. Optimal blood drug levels are influenced by type of transplant, patient response, time post-transplant, co-administration of other drugs, and drug formulation. The following peak ranges are suggested guidelines:
de novo 1500-1700 mcg/L
<6 Months 800-1000 mcg/L
6-12 Months 600-800 mcg/L
>1 Year 300-600 mcg/L

Clinical Significance

Cyclosporine (Cyclosporin A) is an immunosuppressant therapeutic agent used in the prevention of organ graft rejection. Clinical measurement of blood levels is required due to the inter-individual variability of metabolism as well as the toxicity associated with excessive dosage.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.