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Glypican 3, IHC without Interpretation
Test Code90212
CPT Codes
88342
Preferred Specimen
Formalin-fixed, paraffin-embedded tissue block
Other Acceptable Specimens
Minimum: 3 unstained, positively (+) charged slides
Transport Container
IHC Specimen Transport Kit
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable
Refrigerated: Indefinitely
Frozen: Unacceptable
Methodology
Immunohistochemistry
Setup Schedule
Set up: Mon-Fri; Report available: Next day
Clinical Significance
Glypican 3 (GPC3) is most commonly used in the
differential diagnosis of hepatocellular carcinoma (HCC)
or hepatoblastoma, which overexpress GPC3 compared to
cirrhotic liver or other non-neplastic liver lesions.
Embryonal germ cell tumor and Wilms tumor also
overexpress glypican 3.
differential diagnosis of hepatocellular carcinoma (HCC)
or hepatoblastoma, which overexpress GPC3 compared to
cirrhotic liver or other non-neplastic liver lesions.
Embryonal germ cell tumor and Wilms tumor also
overexpress glypican 3.
Performing Laboratory
Quest Diagnostics Nichols Institute |
14225 Newbrook Drive |
Chantilly, VA 20153 |