Steroid Panel, 21-Hydroxylase Deficiency/Stress

Test Code

CPT Codes
83498, 82157, 82533

17-Hydroxyprogesterone, Androstenedione, Cortisol

Preferred Specimen
0.5 mL serum collected in a red-top tube (no gel)

Minimum Volume
0.25 mL

Spin down immediately and pour off into a plastic transport tube.

Transport Container
Plastic screw-cap vial

Transport Temperature

Specimen Stability
Room temperature: 72 hours
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
SST tubes • Gross hemolysis • Moderate hemolysis • Grossly lipemic • Grossly icteric

Chromatography/ Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Sun, Tues; Report available: 5-10 days

Reference Range
See individual tests

Clinical Significance
This panel is of value in pediatric patients to differentiate between CAH (21-hydroxylase deficiency) and acute stress due to other causes.

Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA
33608 Ortega Highway
San Juan Capistrano, CA 92675-2042

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.