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Beta-catenin, IHC with Interpretation

Test Code
90144


CPT Codes
88342

Preferred Specimen
Formalin-fixed, paraffin-embedded tissue block


Other Acceptable Specimens
Minimum: 3 unstained, positively charged slides


Instructions
Please include surgical pathology report.


Transport Container
IHC Specimen Transport Kit


Transport Temperature
Room temperature


Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable


Methodology
Immunohistochemistry

Setup Schedule
Set up: Mon-Fri a.m.; Report available: 3 days


Reference Range
Interpretive report


Clinical Significance
Overexpression of beta-catenin, a cytoplasmic signaling protein, is characteristic of neuroblastoma, in contrast to most other small round blue cell tumors. Desmoid tumors may show both nuclear and cytoplasmic expression for beta-catenin.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.