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A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Glucagon
Test Code519
CPT Codes
82943
Preferred Specimen
2 mL plasma collected in an EDTA (lavender-top) tube
Patient Preparation
Overnight fasting is required
Minimum Volume
0.5 mL
Instructions
Collect EDTA plasma, invert several times to mix, centrifuge, and immediately transfer the plasma into a clean, plastic screw-cap vial and freeze. There should be no delay in freezing as the analyte is very unstable and samples must be kept frozen until testing.
Transport Container
Plastic screw-cap vial
Transport Temperature
Frozen
Specimen Stability
Room temperature: Unacceptable
Refrigerated: 2 hours
Frozen: 28 days
Refrigerated: 2 hours
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Samples received refrigerated • Gross hemolysis
Methodology
Enzyme Linked Immunosorbent Immunoassay (ELISA)
Setup Schedule
Set up: Mon; Report available: 7-14 days
Reference Range
11-78 pg/mL
Clinical Significance
The glucagon assay is useful primarily when considering a glucagon-secreting tumor of the pancreas. Glucagonomas cause an unusual but characteristic syndrome consisting of a rash, mild diabetes, weight loss and hypoamninoacidemia. Measurement of plasma glucagon confirms the diagnosis; glucagon levels are very high in the setting of glucagonoma.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |