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Glypican 3, IHC with Interpretation
Test Code90162
CPT Codes
88342
Preferred Specimen
Formalin-fixed, paraffin-embedded tissue block
Other Acceptable Specimens
3 unstained, positively charged slides
Instructions
Please include surgical pathology report.
Transport Container
IHC Specimen Transport Kit
Transport Temperature
Room temperature
Specimen Stability
Room temperature: Indefinitely
Refrigerated: Indefinitely
Frozen: Unacceptable
Refrigerated: Indefinitely
Frozen: Unacceptable
Methodology
Immunohistochemistry
Setup Schedule
Set up: Mon-Fri; Report available: 3 days
Reference Range
Interpretive report
Clinical Significance
Glypican 3 (GPC3) is most commonly used in the differential diagnosis of hepatocellular carcinoma (HCC) or hepatoblastoma, which overexpress GPC3, as opposed to cirrhotic liver or other non-neoplastic liver lesions. Embryonal germ cell tumor and Wilms tumor also overexpress glypican 3.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153