Amino Acid Analysis for MSUD, Plasma

Test Code

CPT Codes
82136<br /> ** This test code is for non-New York patient testing. For New York patient testing, use test code 19780**


Preferred Specimen
2 mL plasma collected in an EDTA (lavender-top) tube, or a sodium or lithium heparin (green-top) tube

Patient Preparation
Collect plasma specimens after an overnight fast (or at least 4 hours after a meal). Include date of collection and age of patient. (Age must be provided for the interpretation and age related reference ranges to print on the report.

Minimum Volume
0.25 mL

Other Acceptable Specimens

Separate plasma from cells as soon as possible and freeze below -20°C.

Transport Temperature

Specimen Stability
Room temperature: Unacceptable
Refrigerated: 7 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Samples received Room Temperature

Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Mon-Fri a.m.; Report available: 6-9 days

Reference Range
See Laboratory Report

Clinical Significance
Amino acid analysis is necessary for the diagnosis of a variety of inborn errors of metabolism. These include, but are not limited to, phenylketonuria, tyrosimemia, citrullinemia, non-ketotic hyperglycinemia, maple syrup urine disease, and homocystinuria. The assay is also key for the continued monitoring of treatment plans for these disorders and useful for assessing nutritional status of patients. Our methodology is highly accurate at very low levels as well as at elevated levels.

Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92675

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.