11-Deoxycortisol

Test Code
30543

CPT Codes
82634

Preferred Specimen
1 mL serum collected in a red-top tube (no gel)

Patient Preparation
An early morning specimen is preferred.

Minimum Volume
0.25 mL

Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top), or EDTA (royal blue-top), or Sodium heparin (green-top) or, Lithium heparin (green-top)

Instructions
Separate serum after clotting. Ship serum refrigerated or frozen.

Transport Container
Plastic screw-cap vial

Transport Temperature
Frozen

Specimen Stability
Room temperature: 4 days
Refrigerated: 4 days
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube (SST) • Do not submit glass tubes

Methodology
Chromatography/Mass Spectrometry

This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Tues; Report available: 3-10 days

Reference Range
See Laboratory Report

Clinical Significance
11-Deoxycortisol (Compound S) is useful in diagnosing patients with 11-beta-hydroxylase deficiency (second leading cause of congenital adrenal hyperplasia) and primary (adrenal failure) or secondary (hypothalamic-pituitary ACTH deficiency) adrenal insufficiency.

Performing Laboratory
Quest Diagnostics Nichols Inst San Juan Capistrano
33608 Ortega Highway
San Juan Capistrano, CA 92675



The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.