|
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z # |
Cytomegalovirus Antibodies (IgG, IgM)
Test Code6732
CPT Codes
86644, 86645
Preferred Specimen
1.5 mL serum
Minimum Volume
0.7 mL
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 7 days
Frozen: 30 days
Refrigerated: 7 days
Frozen: 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Grossly lipemic • Grossly icteric
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon, Wed, Fri a.m.; Report available: Next day
Limitations
False-positive IgM test results may be due to the presence of heterophil antibodies or presence of rheumatoid factor.
Reference Range
Cytomegalovirus Antibody (IgG)
U/mL | Interpretation |
<0.60 | Negative |
0.60-0.69 | Equivocal |
≥0.70 | Positive |
Cytomegalovirus Antibody (IgM)
AU/mL | Interpretation |
<30.00 | No antibody detected |
30.00-34.99 | Equivocal |
≥35.00 | Antibody detected |
Clinical Significance
Intrauterine or congenital CMV infections occur in 0.5 to 2.2% of all live births. Symptomatic congenital infections usually occur in infants born to non-immune mothers who have primary infections during pregnancy. Latency and reactivation of CMV influence the interpretation of serological results. A single positive CMV IgG result is and indication of present or past infection. The presence of CMV IgM suggests a recent CMV exposure but does not differentiate between primary infection and reactivation.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153