Cobalt, Serum/Plasma [345]

For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.

Test Code

Alias/See Also

CPT Codes

Preferred Specimen
0.5 mL serum collected in a no additive (royal blue-top) tube

Minimum Volume
0.2 mL

Other Acceptable Specimens
Plasma collected in: EDTA (royal blue-top) tube

Collect in a no additive (royal blue-top) tube for serum or an EDTA (royal blue-top) tube for plasma. Then pour into a trace metal-free plastic vial.

Transport Container
Trace metal-free plastic vial

Transport Temperature
Refrigerated (cold packs)

Specimen Stability
Room temperature: 10 days
Refrigerated: 10 days
Frozen: 10 days

Inductively Coupled Plasma/Mass Spectrometry (ICP/MS)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Tues-Sat (evening shifts); Report available: Same day

Reference Range
0.1-0.4 mcg/L

Clinical Significance
Cobalt is essential for humans only as an integral part
of Vitamin B12 (cobalamin). No other function for cobalt
in the human body is known. This provides for normal
reference ranges. Cobalt is found in metal alloys that
are very hard, have high melting points, and are
resistant to oxidation. Occupational exposure occurs
during the production and machining of these metal alloys
and has led to acute and chronic medical conditions.

Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153

Last Updated: November 29, 2021

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.