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Zinc Protoporphyrin (ZPP) [948]
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
ZPP
Alias/See Also
948;
PROTOPORPH ZINC,
ZINC PROTOPORPHYRIN,
ZPP
PROTOPORPH ZINC,
ZINC PROTOPORPHYRIN,
ZPP
CPT Codes
84202
Preferred Specimen
2 mL (0.5 mL minimum; pediatric 0.2 mL minimum) whole blood
collected in an EDTA (tan-top) tube
collected in an EDTA (tan-top) tube
Minimum Volume
0.5 mL • Pediatric specimen: 0.2 mL
Other Acceptable Specimens
Whole blood collected in: EDTA (royal blue-top) tube, sodium heparin (royal blue-top) tube, sodium or lithium heparin (green-top) tube
Instructions
Use a lead-free tube if a blood lead is also requested.
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 4 days
Refrigerated: 10 days
Frozen: Unacceptable
Refrigerated: 10 days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
EDTA lavender top, Hemolysis, Received frozen, Clotted
Methodology
Hematofluorometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Mon-Sat; Report available: 1-2 days
Limitations
Aluminum and anemia of chronic disease may cause elevated results.
Reference Range
Industrial Exposure | <100 mcg/dL |
Clinical Significance
Zinc protoporphyrin (ZPP) accumulates in erythrocytes as a result of chronic lead absorption or iron deficiency anemia.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153
Last Updated: July 11, 2023