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PBG Deaminase, Whole Blood
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
PBGD
Alias/See Also
Acute Intermittent Porphyria (AIP).
MAYO code PBGD
MAYO code PBGD
CPT Codes
82657
Preferred Specimen
4 mL Whole Blood collected in a Sodium Heparin (Green Top) tube
Patient Preparation
Abstinence from alcohol for at least 24 hours prior to specimen collection is essential as ethanol induces porphobilinogen deaminase (PBGD) activity, which may lead to a false-normal result.
Minimum Volume
3 mL
Other Acceptable Specimens
Lavender top K2EDTA tube
or
green top (Lithium Heparin) tube
or
green top (Lithium Heparin) tube
Transport Container
Sodium Heparin Green Top tube
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature: 7 Days
Refrigerated: 8 Days
Frozen: Unacceptable
Refrigerated: 8 Days
Frozen: Unacceptable
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis
Methodology
Enzymatic End point/Spectrofluorometric
Setup Schedule
Tuesday, Thursday
Report Available
2 - 4 days
Clinical Significance
Confirmation of a diagnosis of acute intermittent porphyria (AIP)
Performing Laboratory
MAYO CLINIC LABORATORIES
200 FIRST ST
ROCHESTER, MN 55905
Last Updated: August 4, 2022