Complement, Alternate Pathway, Functional

Message
For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.


Test Code
CMPALT


Alias/See Also
Mayo code AH50


CPT Codes
86161

Preferred Specimen
5 mL Serum from a Red Top tube.


Patient Preparation
Patient should be fasting.

Minimum Volume
0.2 mL


Instructions
Immediately after specimen collection, place the tube on wet ice. Centrifuge at 4 degrees C and aliquot serum into a plastic vial. Freeze specimen within 30 minutes.


Transport Container
Plastic vial


Transport Temperature
Frozen


Specimen Stability
Room Temperature: NA
Refrigerated: NA
Frozen: 14 Days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum in a SST


Methodology
Enzyme-Linked Immunosorbent Assay (ELISA)

Report Available
1 - 7 days


Clinical Significance
Investigation of suspected alternative pathway complement deficiency, atypical hemolytic uremic syndrome, C3 glomerulonephritis, dense-deposit disease


Performing Laboratory
MAYO CLINIC LABORATORIES
3050 SUPERIOR DR NW
ROCHESTER, MN 55901


Last Updated: November 19, 2021


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.