Alpha-1-Antitrypsin (AAT) Phenotype

Message

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Test Code

A1APHN

CPT Codes
82104

Preferred Specimen

1 mL serum

Minimum Volume

0.1 mL

Transport Temperature

Refrigerated (cold packs)

Specimen Stability

Room temperature: 8 hours
Refrigerated: 14 days
Frozen: 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Received room temperature

Methodology
Isoelectrofocusing

Setup Schedule

Monday, Wednesday, Friday Evening Report available: 4 Days

Reference Range

See Laboratory Report

Clinical Significance

More than 40 phenotypes of AAT exist. The inherited deficiency, seen most often as the ZZ, SS and SZ phenotypes, is associated with neonatal hepatitis and infantile cirrhosis. In adults, these phenotypes are associated with chronic lung disease, including emphysema and chronic bronchitis.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Last Updated: November 24, 2021

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.