Substance P

Message

For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.

Test Code

SUBP

CPT Codes
83520

Preferred Specimen

5 mL frozen serum collected in a serum separator tube (SST®)

Minimum Volume

1 mL

Instructions

Collect blood in SST® tube. Allow to clot for 30 minutes at room temperature. Centrifuge sample at 1000 x G for 15 minutes. Separate serum into a transfer tube as soon as possible. Freeze at -20° C immediately.

Transport Container

Plastic, leak-proof transfer tube

Transport Temperature

Frozen

Specimen Stability

Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 28 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Specimens received unfrozen • Refrigerated or ambient • Specimens outside of listed stability • Plasma

Methodology
Enzyme Immunoassay (EIA)

Setup Schedule

Set up: Mon (twice a month); Report available: 21 days

Reference Range

<1700 pg/mL

Clinical Significance

Substance P is a neuropeptide present in the central and peripheral nervous system. Substance P is a neurotransmitter released in response to pain and other noxious stimuli. Substance P is a neuropeptide of the tachykinin class that also includes neurokinin. Substance P is found in the brain, spinal cored, and peripheral tissues and is released from nerve endings in response to stimuli. Increased substance P levels can occur in neurogenic inflammation and physiological stress and may be associated with cardinoid or neuroendocrine tumors.

Performing Laboratory
BioAgilytix Diagnostics
1320 Soldiers Field Rd
Boston, MA 02135

Last Updated: December 6, 2021

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.