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Histoplasma AG, Urine, EIA
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Test Code
HSTAGU
CPT Codes
87385
Preferred Specimen
5 mL Urine
Minimum Volume
1.0 mL
Transport Container
Sterile Urine Cup
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature: N/A
Refrigerated: 3 DAYS
Frozen: UNACCEPTABLE
Refrigerated: 3 DAYS
Frozen: UNACCEPTABLE
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Rejected if stored at room temperature. Frozen specimen.
Methodology
Enzyme Immunoassay (EIA)
Setup Schedule
Monday & Friday;
BS
BS
Report Available
1 - 3 days
Reference Range
SEX AGE Report Normals Units
N/M/F 1000Y <2.0 = Negative EIA Units
2.0 - 2.9 = intermediate EIA Units
> or = to 3.0 = Positive EIA Units
N/M/F 1000Y <2.0 = Negative EIA Units
2.0 - 2.9 = intermediate EIA Units
> or = to 3.0 = Positive EIA Units
Clinical Significance
Histoplasma capsulatum is a pathogenic dimorphic fungus of worldwide distribution which is endemic to the Ohio and Mississippi River valleys in the United States and to certain regions of Central and South America. The definitive diagnosis of Histoplasmosis is the isolation of H. capsulatum by culture from clinical specimens. However, cultures usually take 2 to 4 weeks before identification of fungus is possible. Serological methods offer a rapid alternative to microbiological techniques using immunodiffusion or complement fixation. Unfortunately, anti-H. capsulatum antibody titers remain elevated months or even years after successful therapy, and as a result it may not be possible to differentiate between subacute or inactive infections, chronic active forms, and relapses (frequently seen among AIDS patients). This assay detects the presence of H. capsulatum antigen in body fluids.
Performing Laboratory
CompuNet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine, Ohio 45439
Last Updated: November 22, 2021