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Tramadol and Metabolite Screen, Serum / Plasma
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
TRAMM
Alias/See Also
Ultrex®;
Ultram®
Ultram®
CPT Codes
80373
Includes
Tramadol,
O-Desmethyltramadol
O-Desmethyltramadol
Preferred Specimen
2 mL Serum or Plasma, See instructions
Minimum Volume
0.9 mL
Instructions
Serum: Collect sample in Red top tube
Plasma: Collect sample in Lavender top tube (K3EDTA) or Pink top tube.
Peak serum levels are recommended when monitoring patients because the level in the blood drops so rapidly that many negative results are found at the trough. The peak occurs at 40 to 90 minutes post dose. Promptly centrifuge and separate Serum or Plasma into a plastic screw capped vial.
Plasma: Collect sample in Lavender top tube (K3EDTA) or Pink top tube.
Peak serum levels are recommended when monitoring patients because the level in the blood drops so rapidly that many negative results are found at the trough. The peak occurs at 40 to 90 minutes post dose. Promptly centrifuge and separate Serum or Plasma into a plastic screw capped vial.
Transport Container
Pour off tube
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature: 14 days
Refrigerated: 14 days
Frozen: 11 months
Refrigerated: 14 days
Frozen: 11 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Polymer gel separation tube (SST or PST).
Methodology
High Performance Liquid Chromatography/ Tandem Mass Spectrometry (LC-MS/MS)
Setup Schedule
Varies
Report Available
4 days (If Positive: 7 days)
Clinical Significance
Exclusion Screen
Performing Laboratory
NMS Labs
3701 Welsh Road
Willow Grove, PA 19090-2910
Last Updated: January 11, 2024
