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Cryptococcus Antigen
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
This is the test to order when determining if a patient has Cryptococcosis.
This is the test to order when determining if a patient has Cryptococcosis.
Test Code
CRYBL
Alias/See Also
4561;
Antigen, Cryptococcus (serum);
Antigen, Cryptococcus (serum);
CPT Codes
87327; If Cryptococcal Antigen Screen is Detected, then Cryptococcal Antigen, Latex Titer will be performed at an additional charge (CPT code: 86406)
Preferred Specimen
1 mL serum (minimum 0.5 mL)
Instructions
SST or Red top: Avoid hemolysis. Invert a minimum of 5 times, then allow to clot in an upright position for 30 minutes. Centrifuge the the tube for at least 10 minutes. Keep tightly stoppered.
Transport Container
SST (speckled top), Red top , Plastic Vial (transfer) tube
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature = n/a
Refrigerated = 7 days
Frozen = at least 7 days
Refrigerated = 7 days
Frozen = at least 7 days
Methodology
Lateral flow immunochromatographic test system
Setup Schedule
7 days
BS
BS
Report Available
1 day
Clinical Significance
The encapsulated soil yeast Cryptococcus neoformans causes Cryptococcosis. Pulmonary infection is acquired by inhalation of the organism and is usually subclinical in the immunocompetent host. Dissemination may occur in an immunocompromised patient, often to the meninges.
Performing Laboratory
Compunet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine, OH 45439
Last Updated: January 15, 2024