Cryptococcus Antigen, CSF

For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.

This is the test to order when determining if a patient has Cryptococcosis.

Test Code

Alias/See Also
Antigen, Cryptococcus (CSF)

CPT Codes
87327; If Cryptococcal Antigen Screen is Detected, then Cryptococcal Antigen, Latex Titer will be performed at an additional charge (CPT code: 86406)

Preferred Specimen
1 mL CSF in sterile container. (minimum 0.5 mL)

Transport Container
CSF Collection Tube Kit

Transport Temperature

Specimen Stability
Room Temperature = n/a
Refrigerated = 7 days
Frozen = at least 7 days

Lateral flow immunochromatographic test system

Setup Schedule
7 days

Report Available
1 day

Clinical Significance
The encapsulated soil yeast Cryptococcus neoformans causes Cryptococcosis. Pulmonary infection is acquired by inhalation of the organism and is usually subclinical in the immunocompetent host. Dissemination may occur in an immunocompromised patient, often to the meninges.

Performing Laboratory
Compunet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine, OH 45439

Last Updated: January 15, 2024

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.