Scleroderma Antibodies (SCL-70)

Message
For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.


Test Code
SCLR


Alias/See Also
4942;
Anit-SCL 70;
Anti-Scleroderma;
SCL-70;


CPT Codes
86235

Preferred Specimen
1 mL serum (minimum 0.5 mL) 


Instructions
SST or Red top: Avoid hemolysis. Invert a minimum of 5 times, then allow to clot in an upright position for 30 minutes. Centrifuge the the tube for at least 10 minutes. Keep tightly stoppered.


Transport Container
SST (speckled top), Red top , Plastic Vial (transfer) tube


Transport Temperature
Refrigerated (preferred)


Specimen Stability
Room Temperature = n/a
Refrigerated = 7 days
Frozen = at least 7 days


Methodology
EIA

Setup Schedule
Monday, Wednesday, Friday
BS


Report Available
3 days


Reference Range
SEX AGE Report Normals
N/M/F 1000Y < 20  Negative - No detectable antibody by the ELISA test
    20 - 39  Positive - Weak Positive
    > 40 Positive - Moderate - Strong Positive 


Clinical Significance
Antibodies to Scl-70 are a specific marker for scleroderma and are found in 20-60% of scleroderma patients.


Performing Laboratory
CompuNet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine, OH 45439


Last Updated: November 23, 2021


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.