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Legionella Antigen, Urine
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
LEGUAG
Alias/See Also
8856
CPT Codes
87449
Preferred Specimen
5 mL Urine (minimum 0.5 mL)
Transport Container
Sterile Urine Cup
Transport Temperature
Room Temperature or Refrigerated
Specimen Stability
Room Temperature = 1 day
Refrigerated = 14 days
Frozen = at least 7 days
Refrigerated = 14 days
Frozen = at least 7 days
Methodology
EIA
Setup Schedule
Days Monday - Sunday
BS
BS
Report Available
1 day
Reference Range
SEX | AGE | Report Normals | Units |
N/M/F | 1000Y | Negative | |
This assay is specific for legionella pneumophila serogroup 1 which causes more then 50% of all legionella infections. This assay will not detect infections caused by other legionella species / serogroups. Antigenuria may persist for prolonged periods of time. |
Clinical Significance
The detection of Legionella pneumophila serogroup 1 urine antigens by EIA is highly sensitive and specific. When combined with serum antibody detection and examination of respiratory secretions the urinary antigen test provides optimal diagnosis. Antigenuria can occur 2-3 days after infection and may persist for prolonged periods after treatment.Regardless of whether a urine antigen test is used culture should always be performed because culture diagnosis continues to be the most sensitive and specific means to diagnose legionnaire's disease. Only serogroup 1 is detected by EIA. Culture must be performed to detect other serogroups.
Performing Laboratory
CompuNet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine, OH 45439
Last Updated: November 22, 2021