D-Dimer (Quantitative)

Message
For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.

If unable to process and properly store specimens within 8 hours of collection then call CompuNet transportation for a STAT pick-up at (937) 297-8262 option 1.


Test Code
DDIM


Alias/See Also
74910;
D Dimer;
FSP


CPT Codes
85379

Preferred Specimen
1 plastic (2.7mL) completely filled 3.2% Sodium Citrate (light blue top) tube(s)


Minimum Volume
1 Frozen Capped aliquots of Sodium Citrate plasma (Polypropylene tubes recommended)


Instructions
Use standard venipuncture and disposal techniques.

Collect the required quantity of Sodium Citrate (light blue top) tubes.

If unable to process specimens within 4 hours of collection then call CompuNet transportation for a STAT pick-up at (937) 297-8262 option 1.

Sodium Citrate (light blue top) tube(s):
Process immediately (stable only 8 hours), following instructions below:

Note: We recommend aliquot tubes to be made of polypropylene plastic as this material is safe to freeze at <-70 degreess C.

1. Centrifuge capped Sodium Citrate (light blue top) tubes at 3000 rpm for 10 minutes, or at speed and time required to consistently produce Platelet Poor Plasma (<5/kmm3).

2. Carefully remove the plasma from all Sodium Citrate (light blue top) tubes; avoid disturbing the WBC/buffy coat.
Note: If the plasma shows any hemolysis, it must be recollected.

3. Aliquot at least 1mL of plasma into each aliquot tubes labeled “plasma.” Refer to the Minimum Volume section above for the number of aliquots required per test.

4. Finally, place all aliquots into a <-20°C freezer within 8 hours.
Note: Aliquots must remain frozen until they are picked up by the CompuNet courier. Call CompuNet transportation department if frozen specimen boxes are needed.


Transport Container
Whole blood Sodium Citrate (light blue top) tube(s)
   OR
Frozen - Capped aliquots of Sodium Citrate plasma (Polypropylene tubes recommended)


Transport Temperature
Room Temperature: Whole blood Sodium Citrate (light blue top) tube(s)
Refrigerated: Unacceptable for Sodium Citrate (light blue top) tubes whole blood or capped plasma aliquots
Frozen: Capped aliquots of Sodium Citrate plasma


Specimen Stability
Room Temperature: Whole blood Sodium Citrate (light blue top) tube(s) = 8 hours
Refrigerated: Unacceptable for Sodium Citrate (light blue top) tubes whole blood or capped plasma aliquots
Frozen: Capped aliquots of Sodium Citrate plasma (Polypropylene tubes recommended) <4 weeks at <−20 degrees C


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Rejected for hemolysis, clotted, improper fill, incorrect specimen type, thawed frozen aliquots, refrigerated plasma or blood, expired test tubes, >8 hours old if not processed into separated frozen plasma vials.


Methodology
Photo Optical

Setup Schedule
Daily
RFMVH
Core Lab


Report Available
1 day


Clinical Significance
A test ordered to assist in ruling out the presence of a blood clot in extremities, lung, heart or brain and to suggest or eliminate the need for further testing. The assay may also be used to diagnosis Disseminated Intravascular Coagulation (DIC) and to monitor treatment effectiveness. Certain conditions such as pregnancy, rheumatoid arthritis and the elderly population express increased levels.


Performing Laboratory
CompuNet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine, OH 45439


Last Updated: November 22, 2021


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.