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DHEA Sulfate
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
DHEA
Alias/See Also
402;
DHEA-S;
DHEA SO4;
DHEA-S;
DHEA SO4;
CPT Codes
82627
Preferred Specimen
serum
Minimum Volume
1 mL
Other Acceptable Specimens
plasma from Lithium Heparin (Light Green Top)tube
Instructions
Barrier tubes (serum separator tubes or plasma separator tubes) are preferred. If non-barrier tubes are utilized, the serum/plasma must be removed immediately after centrifuging and placed in a screw-cap transfer tube. Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered. Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.
Transport Container
Original tube preferred, may be sent in a screw-top transfer tube.
Transport Temperature
Room Temperature or Refrigerated
Specimen Stability
Room Temperature = 4 days
Refrigerated = 4 days
Frozen = 2 months
Refrigerated = 4 days
Frozen = 2 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis, Lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, exceeds specimen stability guidelines, contaminated sample.
Methodology
immunoassay
Setup Schedule
24/7
AU
AU
Report Available
daily
Clinical Significance
DHEA-S is the sulfated form of DHEA and is the major androgen produced by the adrenal glands. This test is used in the differential diagnosis of hirsute or virilized female patients and for the diagnosis of isolated premature adrenarche and adrenal tumors. About 10% of hirsute women with Polycystic Ovarian Syndrome (PCOS) have elevated DHEA-S but normal levels of other androgens.
Performing Laboratory
Compunet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine, OH 45439
Last Updated: November 22, 2021