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Folic Acid (Folate, Serum)
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
FOL
Alias/See Also
466;
Folate;
Folate Serum;
Vitamin B9
Folate;
Folate Serum;
Vitamin B9
CPT Codes
82746
Preferred Specimen
serum
Minimum Volume
1 mL
Instructions
Barrier tubes (serum separator tubes) are preferred. If non-barrier tubes are utilized, the serum must be removed immediately after centrifuging and placed in a screw-cap transfer tube.
Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered.
Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.
Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered.
Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.
Transport Container
Original tube preferred, may be sent in a screw-top transfer tube.
Transport Temperature
Room Temperature or Refrigerated
Specimen Stability
Room Temperature = 3 days
Refrigerated = 4 days
Frozen = 1 month
Refrigerated = 4 days
Frozen = 1 month
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis, Lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, exceeds specimen stability guidelines, contaminated sample.
Methodology
immunoassay
Setup Schedule
24/7
AU
AU
Report Available
daily
Clinical Significance
Folic acid deficiency is common in pregnant women, alcoholics, in patients whose diets do not include raw fruits and vegetables, and in people with structural damage to the small intestine. The most reliable and direct method of diagnosing folate deficiency is the determination of folate levels in both erythrocytes and serum. Low folic acid levels, however, can also be the result of a primary vitamin B 12 deficiency that decreases the ability of cells to take up folic acid.
Performing Laboratory
Compunet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine, OH 45439
Last Updated: July 6, 2023