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Creatinine Clearance
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
CRCL
Alias/See Also
70228;
CRCL
CRCL
CPT Codes
82575
Preferred Specimen
serum & 24 hr urine
Instructions
Urine, 24 Hour Collecton: Proper collection of 24-hour urine specimens is essential for accurate test results. Instruct patient thoroughly in the correct procedure. Printed instructions for the patient are available from the laboratory.
1. Unless the physician indicates otherwise, instruct the patient to maintain the usual amount of liquid intake but to consume no alcoholic beverages.
2. During the collection period, place the 24-hour urine container provided by CompuNet in a refrigerator or cool place.
3. Have the patient empty his/her bladder in the morning into the toilet (Do NOT include in the 24-hour collection). Write the date and time of voiding on the container label.
4. Collect the patient;s next voiding and add it as soon as possible to the 24-hour container.
5. Add all subsequent voiding to the container as in Step 4. The last sample collected should be the first specimen voided the following morning at the same time as the previous morning;s first voiding.
Submit a 10 ml aliquot of the 24 hour urine along with the SST tube. Record the 24 hour volume as well as the patient height and weight on the requisition form. Serum sample: Avoid hemolysis. Allow to clot in an upright position for 30 minutes. Centrifuge for 10 minutes. Keep tightly stoppered.
1. Unless the physician indicates otherwise, instruct the patient to maintain the usual amount of liquid intake but to consume no alcoholic beverages.
2. During the collection period, place the 24-hour urine container provided by CompuNet in a refrigerator or cool place.
3. Have the patient empty his/her bladder in the morning into the toilet (Do NOT include in the 24-hour collection). Write the date and time of voiding on the container label.
4. Collect the patient;s next voiding and add it as soon as possible to the 24-hour container.
5. Add all subsequent voiding to the container as in Step 4. The last sample collected should be the first specimen voided the following morning at the same time as the previous morning;s first voiding.
Submit a 10 ml aliquot of the 24 hour urine along with the SST tube. Record the 24 hour volume as well as the patient height and weight on the requisition form. Serum sample: Avoid hemolysis. Allow to clot in an upright position for 30 minutes. Centrifuge for 10 minutes. Keep tightly stoppered.
Transport Container
Original tube preferred, may be sent in a screw-top transfer tube
PLUS
a 24 HR urine container
PLUS
a 24 HR urine container
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature = 2 days
Refrigerated = 6 days
Frozen = 6 months
Refrigerated = 6 days
Frozen = 6 months
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis, Lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, exceeds specimen stability guidelines, contaminated sample.
Methodology
Spectrophotometric
Setup Schedule
24/7
AU
AU
Report Available
daily
Clinical Significance
DHEA-S is the sulfated form of DHEA and is the major androgen produced by the adrenal glands. This test is used in the differential diagnosis of hirsute or virilized female patients and for the diagnosis of isolated premature adrenarche and adrenal tumors. About 10% of hirsute women with Polycystic Ovarian Syndrome (PCOS) have elevated DHEA-S but normal levels of other androgens.
Performing Laboratory
CompuNet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine, OH 45439
Last Updated: November 22, 2021
