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Rheumatoid Factor
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
RF
Alias/See Also
4418;
RA;
RA Factor;
RA Factors;
RA Latex;
RA, Quantitative;
RF;
RF (Rheumatoid Factor);
Rheumatoid Arthritis Titer;
RA;
RA Factor;
RA Factors;
RA Latex;
RA, Quantitative;
RF;
RF (Rheumatoid Factor);
Rheumatoid Arthritis Titer;
CPT Codes
86431
Preferred Specimen
serum
Minimum Volume
0.5 mL
Other Acceptable Specimens
plasma from Lithium Heparin (Light Green Top) tube
Instructions
Barrier tubes (serum separator tubes or plasma separator tubes) are preferred. If non-barrier tubes are utilized, the serum/plasma must be removed immediately after centrifuging and placed in a screw-cap transfer tube.
Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered.
Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.
Collection notes: Avoid hemolysis. Invert tubes at least 8 times. Allow to clot in an upright position for 30 minutes. Within 2 hours, centrifuge tubes 10 minutes. Keep tightly stoppered.
Do NOT re-centrifuge tubes. Do NOT freeze the primary collection tube.
Transport Container
Original tube preferred, may be sent in a screw-top transfer tube.
Transport Temperature
Refrigerated
Specimen Stability
Room Temperature = 1 day
Refrigerated = 8 days
Frozen = 4 weeks
Refrigerated = 8 days
Frozen = 4 weeks
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolysis, Lipemia, incorrect specimen type, insufficient sample volume, improper storage conditions, exceeds specimen stability guidelines, contaminated sample.
Methodology
immunoturbometric
Setup Schedule
DAILY
AU
AU
Report Available
daily
Clinical Significance
RF may be elevated in multiple conditions: SLE, rheumatoid arthritis, scleroderma, Sjögren's Syndrome, leprosy, tuberculosis, syphilis, malignancy, thyroid disease and in a significant percentage of otherwise normal elderly patients.
Performing Laboratory
Compunet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine, OH 45439
Last Updated: November 23, 2021
