Heterophile, Mono Screen

Message

For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.

Test Code

MSPT

Alias/See Also

654;
Mono Screen;
Hetero;
Heterophile;
Heterophile Agglutinins;
Heterophile Antibody Screen;
Heterophile Monospot;
Heterophile Screen;
Heterophile Qual;
Infectious Mono;
Infectious Mononucleosis;

CPT Codes
86308

Preferred Specimen

1 mL serum (minimum 0.5 mL)

Instructions

SST or Red top: Avoid hemolysis. Invert a minimum of 5 times, then allow to clot in an upright position for 30 minutes. Centrifuge the the tube for at least 10 minutes. Keep tightly stoppered.

Transport Container

SST (speckled top), Red top , Plastic Vial (transfer) tube

Transport Temperature

Refrigerated (preferred)

Specimen Stability

Room Temperature = n/a
Refrigerated = at least 8 days
Frozen = 1 month

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Rejected for gross hemolysis and lipemia

Methodology
Latex Agglutination

Setup Schedule

Daily
BS

Report Available

1 day

Reference Range

SEX	AGE	Report Normals	Units
N/M/F	1000Y	Negative

Clinical Significance

Heterophile antibodies, in patients with infectious mononucleosis, may be present as early as the fourth day of illness, and by the twenty-first day of illness, 90% of patients will exhibit a positive test. The Epstein-Barr virus causes infectious mononucleosis.

Performing Laboratory
CompuNet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine, OH 45439

Last Updated: November 22, 2021

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.