Varicella-Zoster Virus IgG Antibody

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Test Code
VRCZ


Alias/See Also
4439;
Varicella Zoster IgG;
Varicella IgG Antibodies;
VZV (comment: If ordered with MMR);


CPT Codes
86787

Preferred Specimen
2 mL serum (SST). (minimum 0.5 mL)


Instructions
SST or Red top: Avoid hemolysis. Invert a minimum of 5 times, then allow to clot in an upright position for 30 minutes. Centrifuge the tube for at least 10 minutes. Keep tightly stoppered.


Transport Container
SST (speckled top), Red top , Plastic Vial (transfer) tube


Transport Temperature
Refrigerated (preferred)


Specimen Stability
Room Temperature = n/a
Refrigerated = 7 days
Frozen = at least 7 days


Methodology
Immunoassay

Setup Schedule
Tuesday - Thursday only
BS


Report Available
6 days


Reference Range
SEX AGE Report Normals Units
N/M/F 1000Y < OR = 90 Negative  No VZV IgG antibody detected
    0.91 - 1.09 Equivocal  
    > OR = 1.10 Positive VZV IgG antibody detected
A positive result indicates that the patient has antibody to VZV.  It does not differentiate between an active or past infection.  The clinical diagnosis must be interpreted in conjunction with the clinical signs and symptoms of the patient.  The presence of IgG VZV antibody is consistent with immunity. 


Clinical Significance
Varicella-Zoster Virus (VZV) is a DNA virus of the herpes virus group that causes chicken pox (varicella) and shingles (zoster). Serologic screening of direct health care providers and individuals in high risk groups is needed to avoid spread of infection. Demonstration of VZV IgG antibody in a single serum is consistent with immunity.


Performing Laboratory
Compunet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine, OH 45439


Last Updated: November 23, 2021


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.