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Varicella-Zoster Virus IgG Antibody
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
VRCZ
Alias/See Also
4439;
Varicella Zoster IgG;
Varicella IgG Antibodies;
VZV (comment: If ordered with MMR);
Varicella Zoster IgG;
Varicella IgG Antibodies;
VZV (comment: If ordered with MMR);
CPT Codes
86787
Preferred Specimen
2 mL serum (SST). (minimum 0.5 mL)
Instructions
SST or Red top: Avoid hemolysis. Invert a minimum of 5 times, then allow to clot in an upright position for 30 minutes. Centrifuge the tube for at least 10 minutes. Keep tightly stoppered.
Transport Container
SST (speckled top), Red top , Plastic Vial (transfer) tube
Transport Temperature
Refrigerated (preferred)
Specimen Stability
Room Temperature = n/a
Refrigerated = 7 days
Frozen = at least 7 days
Refrigerated = 7 days
Frozen = at least 7 days
Methodology
Immunoassay
Setup Schedule
Tuesday - Thursday only
BS
BS
Report Available
6 days
Reference Range
SEX | AGE | Report Normals | Units |
N/M/F | 1000Y | < OR = 90 Negative | No VZV IgG antibody detected |
0.91 - 1.09 Equivocal | |||
> OR = 1.10 Positive | VZV IgG antibody detected | ||
A positive result indicates that the patient has antibody to VZV. It does not differentiate between an active or past infection. The clinical diagnosis must be interpreted in conjunction with the clinical signs and symptoms of the patient. The presence of IgG VZV antibody is consistent with immunity. |
Clinical Significance
Varicella-Zoster Virus (VZV) is a DNA virus of the herpes virus group that causes chicken pox (varicella) and shingles (zoster). Serologic screening of direct health care providers and individuals in high risk groups is needed to avoid spread of infection. Demonstration of VZV IgG antibody in a single serum is consistent with immunity.
Performing Laboratory
Compunet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine, OH 45439
Last Updated: November 23, 2021