HSV 1/2 IgG, Herpeselect Type Specific Antibody

Message

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Test Code

HSV12

Alias/See Also

6447;
Herpes I & II Acute / Convalescent;
Herpes I & II, IgG Antibody;
Herpes I and II;
Herpes IgG 1 & 2;
Herpes Simplex;
Herpes Virus Titer 1 & 2;
Herpes (comment: serum);

CPT Codes
86695;86696

Preferred Specimen

1 mL serum (minimum 0.5 mL)

Instructions

SST or Red top: Avoid hemolysis. Invert a minimum of 5 times, then allow to clot in an upright position for 30 minutes. Centrifuge the the tube for at least 10 minutes. Keep tightly stoppered.

Transport Container

SST (speckled top), Red top , Plastic Vial (transfer) tube

Transport Temperature

Refrigerated (preferred)

Specimen Stability

Room Temperature = n/a
Refrigerated = 7 days
Frozen = at least 7 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Rejected for gross hemolysis and lipemia

Methodology
Immunoassay

Setup Schedule

Tuesday and Thursday
BS

Report Available

6 days

Clinical Significance

Herpes Simplex Virus (HSV) is responsible for several clinically significant human viral diseases, with severity ranging from inapparent to fatal. Clinical manifestations include genital tract infections, neonatal herpes, meningoencephalitis, keratoconjunctivitis, and gingivostomatitis. There are two HSV serotypes that are closely related antigenically. HSV type 2 is more commonly associated with genital tract and neonatal infections, while HSV type 1 is more commonly associated with infections of non-genital sites. Specific typing is not usually required for diagnosis or treatment. The mean time to seroconversion using the type specific assay is 25 days. The performance of this assay has not been established for use in a pediatric population, for neonatal screening, or for testing of immunocompromised patients.

Performing Laboratory
CompuNet Clinical Laboratories, LLC
2308 Sandridge Drive
Moraine, OH 45439

Last Updated: November 22, 2021

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.