ColoVantage® (Methylated Septin 9) [16983]

Message
For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.


Test Code
COLVNT


Alias/See Also
16983


CPT Codes
81327<br /> **This test is for non-New York State patient testing only. For New York patient testing, use 16984, ColoVantage&reg; (Methylated Septin 9) (NY).**

Preferred Specimen
10 mL frozen plasma collected in an EDTA (lavender-top) tube


Minimum Volume
5 mL


Instructions
This test requires 10 mL of plasma (minimum volume 5 mL). Specimens with less than 5 mL of plasma will be rejected. To obtain this volume of plasma, collect blood in two (2) 10 mL EDTA (lavender-top) tubes or five (5) standard EDTA (lavender-top) tubes. Centrifuge the blood samples, separate plasma and combine them. Send plasma in a single 10 mL pour-off tube. If a 10 mL pour-off tube is not available, two (2) 5 mL pour-off tubes can be used.


Transport Container
Plastic screw-cap vial


Transport Temperature
Frozen


Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 28 days


Methodology
Real-Time Polymerase Chain Reaction

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Daily a.m.; Report available: 3 days


Reference Range

Not detected



Clinical Significance
Methylated Septin 9 is a DNA marker associated with colorectal cancer.


Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153


Last Updated: November 29, 2021


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.