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Protein Total and Protein Electrophoresis, CSF [749]
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
PECSF
Alias/See Also
749;
PEP (CSF)
PEP (CSF)
CPT Codes
84157, 84166
Includes
Protein, Total, CSF
Protein Electrophoresis, CSF
Protein Electrophoresis, CSF
Preferred Specimen
6 mL CSF collected in a sterile, leak-proof CSF container
Minimum Volume
3.5 mL
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room temperature: 48 hours
Refrigerated: 7 days
Frozen: 28 days
Refrigerated: 7 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis
Methodology
Agarose Gel Electrophoresis • Spectrophotometry (SP)
Setup Schedule
Set up: Mon-Sat; Report available: 3-5 days
Reference Range
Protein, Total, CSF
| <1 month | 15-100 mg/dL |
| 1 month-60 years | 15-45 mg/dL |
| >60 years | 15-60 mg/dL |
| Prealbumin | 1.3-6.9 % |
| Albumin | 51.9-67.8 % |
| Alpha-1-Globulin | 1.8-6.5 % |
| Alpha-2-Globulin | 4.6-10.8 % |
| Beta Globulin | 7.8-18.2 % |
| Gamma Globulin | 4.8-17.6 % |
Clinical Significance
To evaluate protein composition of cerebrospinal fluid and may be useful in neurological diseases or tumors in central nervous system. This assay is not recommended for the assessment of multiple sclerosis for which oligoclonal bands in CSF and serum should be ordered.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Dr
Chantilly, VA 20153
Last Updated: April 18, 2023
