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Vitamin B2 (Riboflavin), Plasma [36399]

Message
For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.


Test Code
VITB2


Alias/See Also
36399


CPT Codes
84252

Preferred Specimen
2 mL frozen plasma collected in an EDTA (lavender-top) tube - protect from light. Specimen cannot be used for multiple tests. If other vitamin tests are ordered, draw tubes for each vitamin requested.


Patient Preparation
Overnight fasting is required. Avoidance of vitamin supplements for 24 hours prior to collection is preferred.

Minimum Volume
0.5 mL


Other Acceptable Specimens
Frozen plasma collected in a light protected EDTA (lavender-top) tube


Instructions
Pour serum or plasma into amber transport tube (preferred) or transport tube wrapped in aluminum foil to protect from light.


Transport Temperature
Frozen


Specimen Stability
Room temperature: Unacceptable
Refrigerated: Unacceptable
Frozen: 30 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum separator tube


Methodology
Chromatography/Mass Spectrometry

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule
Set up: Tues-Sat; Report available: 3-4 days


Reference Range
6.2-39.0 nmol/L


Clinical Significance
Vitamin B2 is involved in metabolism of fats, carbohydrates, and protein. The clinical manifestations of deficiency are non-specific. Clinical manifestations include mucocutaneous lesions of the mouth and skin, corneal vascularization, anemia, and personality changes.


Performing Laboratory
Quest Diagnostics Nichols Institute Valencia
27027 Tourney Road
Valencia, CA 91355-5386


Last Updated: December 7, 2021


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.