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Collagen Type I C-Telopeptide (CTx)
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
A minimum of 12 hours fasting is required. Fasting morning collections 8-10 am (Diurnal variations cause elevated levels at night).
Patient Preparation: Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
A minimum of 12 hours fasting is required. Fasting morning collections 8-10 am (Diurnal variations cause elevated levels at night).
Patient Preparation: Dietary supplements containing biotin may interfere in assays and may skew results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Test Code
CTELO
Alias/See Also
17406
CPT Codes
82523
Preferred Specimen
1 mL fasting serum
Patient Preparation
Minimum of 12 hours fasting is required. Fasting morning collection 8-10 am. (Diurnal variations cause elevated levels at night.)
Dietary supplements containing biotin may interfere in assays and may skew analyte results to be either falsely high or falsely low. For patients receiving the recommended daily doses of biotin, draw samples at least 8 hours following the last biotin supplementation. For patients on mega-doses of biotin supplements, draw samples at least 72 hours following the last biotin supplementation.
Minimum Volume
0.5 mL
Instructions
Allow blood to clot (30-60 minutes) at room temperature. Centrifuge and separate the serum from the cells and transfer serum to a clean transport tube. Freeze as soon as possible.
Transport Container
Transport tube
Transport Temperature
Frozen
Specimen Stability
Room temperature: 16 hours
Refrigerated: 72 hours
Frozen: 90 days
Refrigerated: 72 hours
Frozen: 90 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Moderate to gross hemolysis • Grossly lipemic • Grossly icteric
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Tues-Sat; Report available: 1-3 days
Reference Range
Adult Male
18-29 Years 87-1200 pg/mL
30-39 Years 70-780 pg/mL
40-49 Years 60-700 pg/mL
50-68 Years 87-345 pg/mL
Adult Female
18-29 Years 60-640 pg/mL
30-39 Years 60-650 pg/mL
40-49 Years 50-465 pg/mL
>49 Years Not established
Pediatric Male
5-9 Years 574-1849 pg/mL
10-13 Years 519-2415 pg/mL
14-17 Years 435-2924 pg/mL
Pediatric Female
5-9 Years 574-1849 pg/mL
10-13 Years 519-2415 pg/mL
14-17 Years 242-1291 pg/mL
18-29 Years 87-1200 pg/mL
30-39 Years 70-780 pg/mL
40-49 Years 60-700 pg/mL
50-68 Years 87-345 pg/mL
Adult Female
18-29 Years 60-640 pg/mL
30-39 Years 60-650 pg/mL
40-49 Years 50-465 pg/mL
>49 Years Not established
Pediatric Male
5-9 Years 574-1849 pg/mL
10-13 Years 519-2415 pg/mL
14-17 Years 435-2924 pg/mL
Pediatric Female
5-9 Years 574-1849 pg/mL
10-13 Years 519-2415 pg/mL
14-17 Years 242-1291 pg/mL
Clinical Significance
CTx is useful to assess bone resorption in patients with metabolic bone disease. The test is also useful in monitoring therapy to slow or halt osteoporotic bone loss.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153
Last Updated: May 22, 2024
