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Beta-2-Microglobulin, Urine [4944X]
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
BTA2MC
Alias/See Also
4944
CPT Codes
82232
Includes
CPT code 81050 may be added at an additional charge for volume measurement
Preferred Specimen
10 mL urine collected in a Quest Diagnostic Beta-2 Microglobulin Transport tube (available through purchasing). If tube is unavailable, see step 5 of Instructions below.
Minimum Volume
10 mL
Other Acceptable Specimens
See Instructions
Instructions
1. Patient should void bladder, then drink at least 500 mL (approximately 17 oz) of water.
2. A urine sample should be collected within 1 hour.
3. Pour exactly 10 mL of random urine into a Quest Diagnostics Beta-2 Microglobulin Transport Tube (available through Client Supply).
4. Ship room temperature.
5. Alternatively, if the collection tubes are not available, the specimen pH must be adjusted to between 6 and 8 using 1N NaOH prior to shipping.
Beta-2 Microglobulin in urine is unstable in acidic urine (pH less than 6). Exactly 10 mL of urine in the Quest Diagnostics Beta-2 Microglobulin Transport Tube is required to achieve the required pH of between 6 and 8. Any volume above or below 10 mL will result in a pH that is outside the acceptable range.
2. A urine sample should be collected within 1 hour.
3. Pour exactly 10 mL of random urine into a Quest Diagnostics Beta-2 Microglobulin Transport Tube (available through Client Supply).
4. Ship room temperature.
5. Alternatively, if the collection tubes are not available, the specimen pH must be adjusted to between 6 and 8 using 1N NaOH prior to shipping.
Beta-2 Microglobulin in urine is unstable in acidic urine (pH less than 6). Exactly 10 mL of urine in the Quest Diagnostics Beta-2 Microglobulin Transport Tube is required to achieve the required pH of between 6 and 8. Any volume above or below 10 mL will result in a pH that is outside the acceptable range.
Transport Temperature
Room Temperature
Specimen Stability
Room Temperature = 5 days
Refrigerated = 15 days
Frozen = 30 days
Refrigerated = 15 days
Frozen = 30 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Specimens received in a non-Beta-2 Microglobulin transport tube with a pH less than 6 • Any volume other than 10 mL urine in the transport tube • Any specimen with pH less than 6
Methodology
Immunoturbidimetric
Setup Schedule
Monday - Saturday
Report Available
3 days
Reference Range
| <18 Years | Not established |
| Adults | ≤0.20 mg/L |
Clinical Significance
Alternatively, if the collection tubes are not available, the specimen pH must be adjusted to between 6 and 8 using 1N NaOH prior to shipping.
1. Patient should void bladder, then drink at least 500 mL (approximately 17 oz) of water.
2. A urine sample should be collected within 1 hour.
3. Pour exactly 10 mL of random urine into a Quest Diagnostics Beta-2 Microglobulin Transport Tube (available through Client Supply).
4. Ship room temperature.
5. Alternatively, if the collection tubes are not available, the specimen pH must be adjusted to between 6 and 8 using 1N NaOH prior to shipping.
Beta-2 Microglobulin in urine is unstable in acidic urine (less than pH
6). Exactly 10 mL of urine in the Quest Diagnostics Beta-2 Microglobulin Transport Tube is required to achieve the required pH of between 6 and 8. Any volume above or below 10 mL will result in a pH that is outside the acceptable range.
1. Patient should void bladder, then drink at least 500 mL (approximately 17 oz) of water.
2. A urine sample should be collected within 1 hour.
3. Pour exactly 10 mL of random urine into a Quest Diagnostics Beta-2 Microglobulin Transport Tube (available through Client Supply).
4. Ship room temperature.
5. Alternatively, if the collection tubes are not available, the specimen pH must be adjusted to between 6 and 8 using 1N NaOH prior to shipping.
Beta-2 Microglobulin in urine is unstable in acidic urine (less than pH
6). Exactly 10 mL of urine in the Quest Diagnostics Beta-2 Microglobulin Transport Tube is required to achieve the required pH of between 6 and 8. Any volume above or below 10 mL will result in a pH that is outside the acceptable range.
Performing Laboratory
Quest Diagnostics Nichols Institute
14225 Newbrook Drive
Chantilly, VA 20153
Last Updated: October 4, 2022
