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11-Deoxycortisol
MessageFor Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.
Test Code
11DEOX
Alias/See Also
30543
CPT Codes
82634
Preferred Specimen
1 mL serum
Minimum Volume
0.5 mL
Other Acceptable Specimens
Plasma collected in: EDTA (lavender-top) tube, EDTA (royal blue-top) tube, or sodium heparin (green-top) tube
Instructions
Separate serum after clotting. An early morning specimen is preferred.
Transport Container
Transport tube
Transport Temperature
Refrigerated (cold packs)
Specimen Stability
Room Temperature = 4 days
Refrigerated = 4 days
Frozen = 4 weeks
Refrigerated = 4 days
Frozen = 4 weeks
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Serum Separator Tubes (SST); Glass Tubes
Methodology
Chromatography/Mass Spectrometry
FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by the U.S. Food and Drug Administration. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.
Setup Schedule
Set up: Tues; Report available: 3-10 days
Report Available
2 days
Reference Range
See Laboratory Report
Clinical Significance
11-Deoxycortisol (Compound S) is useful in diagnosing patients with 11-beta-hydroxylase deficiency (second leading cause of congenital adrenal hyperplasia) and primary (adrenal failure) or secondary (hypothalamic-pituitary ACTH deficiency) adrenal insufficiency.
Performing Laboratory
| Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
| 33608 Ortega Highway |
| San Juan Capistrano, CA 92675-2042 |
Last Updated: May 17, 2024
