14-3-3 eta Protein [91455]

Message

For Specimen Integrity during Extreme Weather see the “Lockbox Usage in Extreme Weather” document at the top of this page.

Test Code

1433PR

Alias/See Also

91455

CPT Codes
83520

Preferred Specimen

1 mL serum

Minimum Volume

0.5 mL

Instructions

Allow blood to clot (10-15 minutes) at room temperature. Centrifuge and
separate from cells. Ship refrigerated.

Transport Temperature

Room temperature

Specimen Stability

Room temperature: 7 days
Referigerated: 7 days
Frozen: 21 days

Methodology
Enzyme Linked Immunosorbent Assay (ELISA)

FDA Status
This test was developed and its analytical performance characteristics have been determined by Quest Diagnostics. It has not been cleared or approved by FDA. This assay has been validated pursuant to the CLIA regulations and is used for clinical purposes.

Setup Schedule

Set up: Mon, Wed, Sat; Report available: 4-8 days

Reference Range

<0.2 ng/mL

Clinical Significance

14-3-3 eta protein is released into the circulation as part of the pathological process of joint inflammation and joint erosion in rheumatoid arthritis (RA) and psoriatic arthritis. Concentrations are significantly higher in people with active joint disease than in those with inactive RA or psoriasis without arthritis. An elevated 14-3-3 eta level supports the diagnosis of RA and can help predict disease severity.

Performing Laboratory

Quest Diagnostics Nichols Institute-San Juan Capistrano, CA

33608 Ortega Highway

San Juan Capistrano, CA 92675-2042

Last Updated: December 7, 2021

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.