RAPAMYCIN (Sirolimus)

Message

Draw sample just before next dose. DO NOT CENTRIFUGE. This test is not performed on weekends.

Test Code

RAPA

CPT Codes
80195

Preferred Specimen

1 Lavender tube (EDTA)

Minimum Volume

0.5 mL

Other Acceptable Specimens

None

Instructions

Do not centrifuge. Refrigerate until tested.

Transport Temperature

Refrigerate

Specimen Stability

15-30ºC up to 24 hours; 2-8ºC Refrigerate up to 7 days; Frozen up to 2 months

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

The following will be rejected: Serum, plasma, or clotted samples. Samples left at room temperature >24 hours will be rejected.

Methodology

Quantitative High Performance Liquid Chromotography - Tamdem Mass Spectrometry

Setup Schedule

M, Tu, W, Th, F

Reference Range

Kidney tranplant in combination with Cyclosporine: 4-12 ng/mL

Liver transplant: 12-20 ng/mL

Optimal therapeutic range for a given patient may differ from this suggested range based on the indication for therapy, treatment phase, use in combination with other drugs, time or specimen collection relative to prior dose and type of transplanted organ.

Clinical Significance

This test aids in the management of Rapamycin (Sirolimus) therapy in transplant patients.

Performed By
Alverno Laboratories

Performing Laboratory
Alverno Central Lab
NCHMS (LC/MS/MS, Mass Spec)

Last Updated: April 25, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.