THYROID AUTOANTIBODY PROFILE

Test Code

THYRP

CPT Codes
86376, 86800

Includes

Thyroperoxidase antibody (TPO) and Thyroglobulin antibody (Anti-Tg)

Preferred Specimen

1 Gold tube (gel separator)

Minimum Volume

2 mL

Other Acceptable Specimens

or 1 Green tube (Lithium Heparin)

Instructions

Centrifuge for complete separation of plasma/serum and red cells. See Specimen Container for appropriate sample type. Separate and refrigerate or freeze within two (2) hours of collection time.

Specimen Stability

2-8°C up to 3 days; otherwise freeze

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolyzed or lipemic samples

Methodology
EIA (Enzyme Immunoassay)

Setup Schedule

M, W, F (day shift only)

Clinical Significance

TPO is an enzyme that binds iodine to thyroglobulin to form the base of thyroid hormones T3 and T4. The detection of antibodies against TPO and thyroglobulin can occur in autoimmune thyroid disease.

Performed By
Alverno Laboratories

Performing Laboratory
Alverno Central Lab
NCHB2 (Chemistry, Beckman DxI)

Last Updated: April 25, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.