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ANTI SMITH ANTIBODY

Test Code
SM


CPT Codes
86235

Preferred Specimen
1 Gold tube (gel separator)
 


Minimum Volume
0.5 mL


Other Acceptable Specimens
or 1 Lavender tube (EDTA)

or 1 Green tube (Lithium Heparin)



Instructions
Centrifuge for complete separation of plasma/serum and red cells. See Specimen Container for appropriate sample type. Separate and refrigerate until tested.


Specimen Stability
  • 2-8°C up to 7 days
  • -20° or lower frozen samples are stable


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Hemolyzed or lipemic samples


Methodology
Multiplex Flow Immunoassay

Setup Schedule
M, T, W, Th, F, Sa, Sun


Clinical Significance
Antibodies to Sm are highly specific for systemic lupus erythematosus and when present are considered a marker antibody. However, these antibodies are found in only 20% of patients with SLE.


Performed By
Alverno Laboratories

Performing Laboratory
Alverno Central Lab  
NIM5 (Immunology, Bioplex)


Last Updated: April 25, 2023


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.