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T4 TOTAL
MessageCentrifuge within 2 hours of collection.
Test Code
T4
Alias/See Also
T4T;Syn-Thyroid;T4;T4 Total Only, T4, Serum;Tetraiodothyronine;Thyroid Hormone;Thyroxine (T4);Total T4
CPT Codes
84436
Preferred Specimen
1 Gold tube (gel separator)
Minimum Volume
0.2 mL
Other Acceptable Specimens
or 1 Green tube (Lithium Heparin)
Instructions
Centrifuge for complete separation of plasma or serum and red cells within 2 hours.
Transport Temperature
Refrigerate
Specimen Stability
- 2-8°C up to 7 days
- 15-30°C up to 8 hours
- Frozen samples are stable
Methodology
Chemiluminescent immunoassay
Setup Schedule
M, T, W, Th, F, Sa, Sun
Reference Range
5.0 - 12.3 ug/dL
Clinical Significance
Total T4 aids in the diagnosis of hyper/hypothyroidism. In conjunction with TSH can determine if the feedback loop is intact. Includes both free and bound T4 and is affected by protein levels. Total thyroxine only provides correct information when the thyroxine-binding capacity in serum is normal.
Performed By
Alverno Laboratories
Performing Laboratory
Alverno Central Lab
NCHB2 (Chemistry, Beckman DxI)
Last Updated: April 25, 2023