HERPES SIMPLEX VIRUS 1/2 IgG ANTIBODY, WITH TITER

Test Code

HSG12

Alias/See Also

HSV Glycoprotein G

CPT Codes
86695, 86696

Includes

Includes: Herpes simplex I, IgG and Herpes simplex II, IgG

Preferred Specimen

1 Gold tube (gel separator)

Minimum Volume

0.5 mL

Other Acceptable Specimens

or 1 Red tube

Instructions

Centrifuge for complete separation of plasma/serum and red cells. See Specimen Container for appropriate sample type. Refrigerate until tested.

Specimen Stability

2-8°C up to 2 days; otherwise freeze at -20° or lower

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolyzed or lipemic samples

Methodology
Multiplex Flow Immunoassay

Setup Schedule

M, Tu, W, Th, F, Sa, Su

Reference Range

Negative: <0.9
Indeterminate: 0.9 - 1.0
Positive: >/= 1.1

This assay is type-specific and will differentiate between HSV 1 and HSV 2 infections. A single positive result only indicates previous immunologic exposure. The performance of this assay has not been established for pediatric populations, for neonatal screening, or for the testing of immunocompromised patients. Levels early in the course of infection may not have detectable levels of HSV IgG. Test cannot differentiate between recent and old infections.

Clinical Significance

HSV Type 1 is associated with lesions above the waist; HSV Type 2 is sexually transmitted and is a cause of generalized infections of the newborn. Also useful in undiagnosed congenital diseases and etiology of prolonged fever in immunosupressed patients.

Performed By
Alverno Laboratories

Performing Laboratory
Alverno Central Lab
NIM5 (Immunology, Bioplex)

Last Updated: April 25, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.