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THYROXINE, FREE
MessageNote: This test is sensitive to Biotin and result may be falsely elevated in patients taking high doeses.
Test Code
T4F
Alias/See Also
FT4; Free Thyroxine; Thyroid; Free T4
CPT Codes
84439
Preferred Specimen
1 Gold tube (gel separator)
Minimum Volume
0.2 mL
Other Acceptable Specimens
or 1 Green tube (Lithium Heparin)
Instructions
Centrifuge for complete separation of serum or plasma and red cells within 2 hours.
Transport Temperature
Refrigerate
Specimen Stability
- 2-8°C up to 7 days
- 15-30°C up to 8 hours
- Frozen samples are stable - do not freeze whole blood
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Quantity not sufficient
Methodology
Chemiluminescent immunoassay
Setup Schedule
M, T, W, Th, F, Sa, Sun
Report Available
Within 24 hours of receipt at the performing laboratory.
Reference Range
Age | ng/dL |
0-3 days | 0.70 - 2.70 |
4 - 29 days | 0.80 - 3.10 |
1-23 months | 0.60 - 2.12 |
2 - 6 years | 0.60 - 1.60 |
7 - 11 years | 0.60 - 1.50 |
12 - 17 years | 0.60 - 1.40 |
Adult | 0.55 - 1.60 |
Clinical Significance
FT4 aids in the diagnosis of hyper/hypothyroidism. In conjunction with TSH can determine if the feedback loop is intact. Includes only FT4 and is unaffected by protein levels.
Performed By
Alverno Laboratories
Performing Laboratory
Alverno Central Lab
NCHB2 (Chemistry, Beckman DxI)
Last Updated: June 7, 2023