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NONHODGKIN LYMPHOMA PANEL by FISH

Message

Must include Hematopathology Patient Information Sheet with order.  Form is linked in the Additional Information below, in the Resources section, on our website, or by calling Client Services at 219-989-3700.




Test Code
NHLFH


Alias/See Also
NHL


CPT Codes
88377 x8

Includes
  • Includes Pathologist Interpretation
  • Rearrangements of ALK, BCL6, MYC, IgH, and MALT1
  • Translocations: MYC/IgH, CCND1/IgH, BCL2/IgH, and Trisomy 8


Preferred Specimen
Bone marrow or whole blood:  1 Green tube (Sodium Heparin)   Note:  Heparin choice is Sodium - do not use Lithium heparin
Lymph node or biopsy:  RPMI
 


Minimum Volume
  • Bone marrow: 1 mL
  • Whole blood: 1 mL
  • Lymph node or tissue: 5x5 mm


Other Acceptable Specimens
1 Lavender tube


Instructions
Must include Hematopathology Patient Information Sheet with order.  Form is linked in the Additional Information below, in the Resources section, on our website, or by calling Client Services at 219-989-3700.


Transport Temperature
Whole blood or bone marrow: Room temperature
Lymph node or tissue: Refrigerate


Specimen Stability
Whole blood or bone marrow:
  • 15-30°C up to 2 days
  • Refrigerated samples will be accepted, but not preferred
Lymph node or tissue:
  • 2-8°C in RPMI up to 2 days


Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Clotted or Frozen samples.
Irretrievable samples will not be rejected.


Methodology
FISH (Fluorescent In Situ Hybridization)

Setup Schedule
Batched


Clinical Significance
This test aids in the diagnosis and classification of b-cell lymphoma and monitoring the response to therapy or progression of disease.


Performed By
Alverno Laboratories

Performing Laboratory
Alverno Central Lab  
NMB15 (Molecular Biology, FISH)

Additional Information
Hematopathology Patient Information Sheet

Last Updated: April 17, 2024


The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.