HEROIN SCREEN w/ CONFIRMAITON

Message

Positive screen will automatically reflex to confirmation testing.

Test Code

HESWC

CPT Codes
80307

Includes

6-acetylmorphine (6-MAM)
Codeine
Morphine

Preferred Specimen

Urine

Minimum Volume

10 mL (1 full yellow tube)

Other Acceptable Specimens

None

Instructions

Refrigerate or freeze specimen

Transport Container

1 Yellow round bottom tube is preferred.
Sterile Container or Alverno Toxi Collection kit (Occupational Medicine accounts) will be accepted.

Transport Temperature

Refrigerate or freeze

Specimen Stability

2-8°C up to 5 days
Frozen samples will be accepted up to 30 days

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

QNS (quantity not sufficient). Samples exposed to repeated freeze/thaw cycles will be rejected.

Methodology
EIA reflex LCMS

Setup Schedule

Screening is performed M, Tu, W, Th, F, Sa, Su
Confirmation testing is performed M, Tu, W, Th, F

Report Available

Screen reported same day tested
Confirmation will be reported 24-48 hours after receipt (M-F only)

Reference Range

Negative

**Drug Screen Cutoff Values**
Drug Name	ng/mL
Heroin	10

Clinical Significance

Heroin is produced by chemical modification of morphine. It is rapidly metabolized (half-life of 9 minutes) to 6- Acetylmorphine (6-AM), and then to morphine by hydrolysis in the liver. The presence of 6-AM cannot be caused by injection of legal opiate analgesics or large quantities of poppy seeds. Positive Chain of Custody screens are kept frozen for 1 year. Positive Non-Chain of Custody screens are kept frozen for 30 days.

Performed By
Alverno Laboratories

Performing Laboratory
Alverno Central Lab
NCHB1 (Chemistry, Beckman AU)

Last Updated: December 12, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.