SCLERODERMA PANEL by MULTIPLEX FLOW IMMUNOASSAY

Test Code

SCLPN

Alias/See Also

ANA; Antinuclear

CPT Codes
86235 x2

Includes

Scl-70 and Centromere B

Preferred Specimen

1 Gold tube (gel separator)

Minimum Volume

0.5 mL

Other Acceptable Specimens

1 Lavender tube (EDTA) or
1 Green tube (Lithium Heparin)

Instructions

Centrifuge for complete separation of plasma or serum and red cells. Separate and refrigerate until tested.

Transport Temperature

Refrigerate

Specimen Stability

2-8°C up to 7 days; otherwise freeze at -20° or lower

Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)

Hemolyzed or lipemic samples will be rejected.

Methodology
Multiplex Flow Immunoassay

Setup Schedule

M, T, W, Th, F, Sa, Sun

Report Available

Within 24 hours of receipt at the performing laboratory.

Reference Range

>1.0 AI

Clinical Significance

This test utilizes a multiplex bead assay to assess the presence of antibodies associated with systemic autoimmune diseases which may be helpful in the diagnosis of scleroderma. The test quantitatively detects Scl-70 and Centromere B.

The test is intended for diagnostic use and is of limited clinical utility in monitoring disease course. If a negative result is obtained in the presence of clinical signs and symptoms suggestive of Scleroderma, repeat testing using an alternative method is suggested (IFA). Positive results can be seen in apparently healthy individuals stressing the importance of clinical correlation with patient signs and symptoms.

Performed By
Alverno Laboratories

Performing Laboratory
Alverno Central Lab
NIM5 (Immunology, Bioplex)

Last Updated: June 8, 2023

The CPT Codes provided in this document are based on AMA guidelines and are for informational purposes only. CPT coding is the sole responsibility of the billing party. Please direct any questions regarding coding to the payor being billed. Any Profile/panel component may be ordered separately. Reflex tests are performed at an additional charge.