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CHRONIC LYMPHOCYTIC LEUKEMIA / SMALL LYMPHOCYTIC LYMPHOMA PANEL by FISH
MessageMust include Hematopathology Patient Information Sheet with order. Form is linked in the Additional Information below, in the Resources section, on our website, or by calling Client Services at 219-989-3700.
Test Code
CLLFH
Alias/See Also
CLL
CPT Codes
88377 x2
Includes
Includes Pathologist Interpretation, ATM deletion, TP53 deletion, D135319 deletion, Trisomy 12
Preferred Specimen
Bone marrow or whole blood: 1 Green tube (Sodium Heparin)
Note: Heparin choice is Sodium - do not use Lithium heparin
Lymph node or biopsy: RPMI
Note: Heparin choice is Sodium - do not use Lithium heparin
Lymph node or biopsy: RPMI
Minimum Volume
- Bone marrow 1 mL
- Whole blood 1 mL
- Tissue or lymph node 5x5 mm
Other Acceptable Specimens
1 Lavender tube (EDTA)
Instructions
Must include Hematopathology Patient Information Sheet with order. Form is linked in the Additional Information below, in the Resources section, on our website, or by calling Client Services at 219-989-3700.
Transport Temperature
Whole blood or bone marrow: Room temperature. Refrigerated samples will be accepted, but not preferred.
Lymph node or tissue: Refrigerate in RPMI
Lymph node or tissue: Refrigerate in RPMI
Specimen Stability
- Whole blood or bone marrow:
- 15-30°C up to 2 days; Refrigerated samples will be accepted, but not preferred.
- Lymph node or tissue:
- 2-8°C in RPMI up to 2 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Clotted samples will be rejected.
Irretrievable samples will not be rejected.
Irretrievable samples will not be rejected.
Methodology
Fluorescence In Situ Hybridization (FISH)
Setup Schedule
Batched
Clinical Significance
This FISH assay uses selected markers for regions of chromosomes 11, 12, 13, and 17 that are useful for prognostic assessment in patients diagnosed by B-cell chronic lymphocytic leukemia.
Performed By
Alverno Laboratories
Performing Laboratory
Alverno Central Lab
NMB15 (Molecular Biology, FISH)
Additional Information
Hematopathology Requisition
Last Updated: November 4, 2024