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Penta Screen
Test CodePENTA
Alias/See Also
15934
CPT Codes
81512<br /> This code is for non-New York clients only. For New York patient testing, use code 16970.
Includes
AFP, unconjugated Estriol, hCG, Dimeric Inhibin A, ITA (hyperglycosylated hCG) and Maternal Risk Interpretation
Preferred Specimen
4 mL serum
Minimum Volume
1.5 mL
Instructions
The risk assessment cannot be performed unless demographic data are provided by the ordering physician.
Transport Container
Plastic screw-cap vial
Transport Temperature
Room temperature
Specimen Stability
Room temperature: 14 days
Refrigerated: 14 days
Frozen: 28 days
Refrigerated: 14 days
Frozen: 28 days
Reject Criteria (Eg, hemolysis? Lipemia? Thaw/Other?)
Gross hemolysis • Gross lipemia
Methodology
Immunoassay (IA)
Setup Schedule
Set up: Mon-Sat; Report available: 3-5 days after receipt at the performing laboratory. Add three (3) days for transport.
Limitations
Penta Screen results consistent with an increased risk of trisomy should be confirmed with amniotic fluid specimen. Results consistent with increased risk of NTD may be followed-up with appropriate diagnostic testing as detailed in the report. Maternal serum screening yields a low percentage of false negatives. A wide range of other chromosomal abnormalities are not identified by maternal serum screening.
Reference Range
See Laboratory Report
Clinical Significance
To screen a woman in her second trimester of pregnancy for Neural Tube Defects, Down Syndrome and Trisomy 18 at 9 to 13 weeks gestation.
Performing Laboratory
Quest Diagnostics Nichols Institute-San Juan Capistrano, CA |
33608 Ortega Highway |
San Juan Capistrano, CA 92675-2042 |
Last Updated: June 22, 2023